You should also be aware that the linked site may be governed by its own set of terms and conditions and privacy policy for which AbbVie has no responsibility. Home What is cholesterol? What are triglycerides? What is LDL cholesterol? What is HDL cholesterol? What do your cholesterol numbers mean? Diet tips for healthy living Exercise tips for healthy living. Tell your doctor about all the prescription and non-prescription medicines you take, including: Aspirin Cholesterol or triglyceride medication Blood pressure medication Anticoagulants, also known as blood thinners Any products containing niacin or nicotinamide Also tell your doctor if you consume large amounts of alcohol.
NIASPAN is also used to lower the risk of heart attack in people who have had a heart attack and have high cholesterol. In people with coronary artery disease and high cholesterol levels, NIASPAN, when used with a bile acid-binding resin another cholesterol medicine , can slow down or lessen the buildup of plaque fatty deposits in your arteries. Do not switch between forms of niacin without talking to your healthcare provider. Tell your healthcare provider about any unexplained muscle pain, tenderness, or weakness, as this could be a sign of a serious side effect.
Your healthcare provider should do blood tests before and during treatment to check liver enzyme levels, as these can increase with treatment. Tell your healthcare provider if you have kidney problems or a history of gout. Do not switch between forms of niacin without talking to your healthcare provider. Tell your healthcare provider about any unexplained muscle pain, tenderness, or weakness, as this could be a sign of a serious side effect.
Your healthcare provider should do blood tests before and during treatment to check liver enzyme levels, as these can increase with treatment. Tell your healthcare provider if you have kidney problems or a history of gout. Talk to your doctor about how the symptoms of flushing are different from symptoms of a heart attack. By dosing at bedtime, flushing will likely occur during sleep. If awakened by flushing, get up slowly, especially if feeling dizzy or faint, or taking blood pressure medications.
If you are taking another cholesterol medication called a bile acid-binding resin e. Tell your healthcare provider about all the medicines you take, including aspirin, any cholesterol medication, blood pressure medication, blood thinner medication, or any products containing niacin or nicotinamide.
For more information, talk with your healthcare provider. Tell your doctor about all the prescription and non-prescription medicines you take, including: Aspirin Cholesterol or triglyceride medication Blood pressure medication Anticoagulants, also known as blood thinners Any products containing niacin or nicotinamide Also tell your doctor if you consume large amounts of alcohol. NIASPAN is also used to lower the risk of heart attack in people who have had a heart attack and have high cholesterol.
After 12 weeks, the researchers noted no significant changes in HbA1c. The mean HbA1c increased from 7. Fasting glucose increased at the week four and eight visits but returned to baseline by the end of the study week Three percent of the patients discontinued niacin due to hyperglycemia. The mean dose of niacin was 2. In this group, fasting glucose increased at the three-month and eight-month visits. Grundy, MD, PhD, conducted a study published in that determined the effectiveness of nicotinic acid in dyslipidemic patients with non-insulin-dependent diabetes.
Patients were assigned to 1. The researchers recommended that nicotinic acid be used with caution in this patient population, and not as a first-line hypolipidemic drug in patients with non-insulin-dependent diabetes. The Coronary Drug Project evaluated use of 3 g per day of immediate release niacin, along with other agents or placebo, in patients with a past myocardial infarction.
No differences were observed in glycosuria or the addition of new diabetes medications in patients receiving niacin vs. Fasting glucose increased modestly and significantly in the niacin-treated group at one year, two years and four years.
After treatment was discontinued, fasting glucose returned to baseline in the niacin-treated group but increased in the placebo group. Subsequent analysis indicated that the long-term cardiovascular benefits of niacin outweighed any effects on glucose.
Thus, when administered at doses of 2. Adverse glycemic effects seem to be most prominent during upward titration of niacin. The effects are often transient and return to near baseline levels after a relatively short time.
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